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Reactogenicity by Vaccine Type

Key Takeaways
H1N1 shows the highest variability and overall severity in reported reactions.
H5N1 generally results in the mildest side effects.
These differences highlight how vaccine type and formulation may influence tolerability.

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Immunogenicity Summary Table

Key Takeaways
H1N1 produces the highest immune response, followed by H7N9 and then H5N1.
Adjuvants like MF59 and AS03 appear frequently in high-response cases.
This table helps explore how vaccine-adjuvant combinations affect immune strength and side effect severity.

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Dataset Description

  • This dataset contains 150 simulated observations generated in R.
  • Variables include vaccine type, adjuvant, GMT fold-change, seroprotection rate (%), and reactogenicity (0–10).
  • The data mimics realistic patterns from immunogenicity and reactogenicity studies.
  • The original dataset from NIH-funded VTEU clinical trials is not public.

Real-World Impact

  • Helps visualize tradeoffs between vaccine safety and efficacy.
  • Useful for informing public health communication and formulation strategy.
  • Source codeView GitHub Repository